@Anton L found another. I will explain.

If site side menu has sub menus.... Say

Groups
   All Groups
   Search
   Top

And you are on any HTMX page enabled, it loads that content within the page. Let me give reproduce instructions.

1. Goto a profile.
2. Open site sidebar menu (left side)
3. Select a menu option with submenu. (We will use groups)
4. Select All groups

At this point it will load the All groups in the profile page htmx section. It doesn't take you to the groups page first.

Hope I explained well enough, if you need further explanation, let me know.